Inflammations of the body come from burnings and inflamings, and all of them originate in bile. When bile finds a means of discharge, it boils up and sends forth all sorts of tumours; but when imprisoned within, it generates many inflammatory diseases, above all when mingled with pure blood; since it then displaces the fibres which are scattered about in the blood and are designed to maintain the balance of rare and dense, in order that the blood may not be so liquefied by heat as to exude from the pores of the body, nor again become too dense and thus find a difficulty in circulating through the veins. The fibres are so constituted as to maintain this balance; and if any one brings them all together when the blood is dead and in process of cooling, then the blood which remains becomes fluid, but if they are left alone, they soon congeal by reason of the surrounding cold. The fibres having this power over the blood, bile, which is only stale blood, and which from being flesh is dissolved again into blood, at the first influx coming in little by little, hot and liquid, is congealed by the power of the fibres; and so congealing and made to cool, it produces internal cold and shuddering. When it enters with more of a flood and overcomes the fibres by its heat, and boiling up throws them into disorder, if it have power enough to maintain its supremacy, it penetrates the marrow and burns up what may be termed the cables of the soul, and sets her free; but when there is not so much of it, and the body though wasted still holds out, the bile is itself mastered, and is either utterly banished, or is thrust through the veins into the lower or upper-belly, and is driven out of the body like an exile from a state in which there has been civil war; whence arise diarrhoeas and dysenteries, and all such disorders. When the constitution is disordered by excess of fire, continuous heat and fever are the result; when excess of air is the cause, then the fever is quotidian; when of water, which is a more sluggish element than either fire or air, then the fever is a tertian; when of earth, which is the most sluggish of the four, and is only purged away in a four-fold period, the result is a quartan fever, which can with difficulty be shaken off.

ὅσα δὲ φλεγμαίνειν λέγεται τοῦ σώματος͵ ἀπὸ τοῦ κάεσθαί τε  καὶ φλέγεσθαι͵ διὰ χολὴν γέγονε πάντα. λαμβάνουσα μὲν οὖν ἀναπνοὴν ἔξω παντοῖα ἀναπέμπει φύματα ζέουσα͵ [85c] καθειργνυμένη δ΄ ἐντὸς πυρίκαυτα νοσήματα πολλὰ ἐμποιεῖ͵ μέγιστον δέ͵ ὅταν αἵματι καθαρῷ συγκερασθεῖσα τὸ τῶν ἰνῶν γένος ἐκ τῆς ἑαυτῶν διαφορῇ τάξεως͵ αἳ διεσπάρησαν μὲν εἰς αἷμα͵ ἵνα συμμέτρως λεπτότητος ἴσχοι καὶ πάχους καὶ μήτε διὰ θερμότητα ὡς ὑγρὸν ἐκ μανοῦ τοῦ σώματος ἐκρέοι͵ μήτ΄ αὖ πυκνότερον δυσκίνητον ὂν μόλις ἀναστρέφοιτο ἐν ταῖς φλεψίν. [85d] καιρὸν δὴ τούτων ἶνες τῇ τῆς φύσεως γενέσει φυλάττουσιν· ἃς ὅταν τις καὶ τεθνεῶτος αἵματος ἐν ψύξει τε ὄντος πρὸς ἀλλήλας συναγάγῃ͵ διαχεῖται πᾶν τὸ λοιπὸν αἷμα͵ ἐαθεῖσαι δὲ ταχὺ μετὰ τοῦ περιεστῶτος αὐτὸ ψύχους συμπηγνύασιν. ταύτην δὴ τὴν δύναμιν ἐχουσῶν ἰνῶν ἐν αἵματι χολὴ φύσει παλαιὸν αἷμα γεγονυῖα καὶ πάλιν ἐκ τῶν σαρκῶν εἰς τοῦτο τετηκυῖα͵ θερμὴ καὶ ὑγρὰ κατ΄ ὀλίγον τὸ πρῶτον ἐμπίπτουσα πήγνυται διὰ τὴν τῶν ἰνῶν δύναμιν͵ [85e] πηγνυμένη δὲ καὶ βίᾳ κατασβεννυμένη χειμῶνα καὶ τρόμον ἐντὸς παρέχει. πλείων δ΄ ἐπιρρέουσα͵ τῇ παρ΄ αὐτῆς θερμότητι κρατήσασα τὰς ἶνας εἰς ἀταξίαν ζέσασα διέσεισεν· καὶ ἐὰν μὲν ἱκανὴ διὰ τέλους κρατῆσαι γένηται͵ πρὸς τὸ τοῦ μυελοῦ διαπεράσασα γένος κάουσα ἔλυσεν τὰ τῆς ψυχῆς αὐτόθεν οἷον νεὼς πείσματα μεθῆκέν τε ἐλευθέραν͵ ὅταν δ΄ ἐλάττων ᾖ τό τε σῶμα ἀντίσχῃ τηκόμενον͵ αὐτὴ κρατηθεῖσα ἢ κατὰ πᾶν τὸ σῶμα ἐξέπεσεν͵ ἢ διὰ τῶν φλεβῶν εἰς τὴν κάτω συνωσθεῖσα ἢ τὴν ἄνω κοιλίαν͵ οἷον φυγὰς ἐκ πόλεως στασιασάσης ἐκ τοῦ σώματος ἐκπίπτουσα͵ [86a] διαρροίας καὶ δυσεντερίας καὶ τὰ τοιαῦτα νοσήματα πάντα παρέσχετο. τὸ μὲν οὖν ἐκ πυρὸς ὑπερβολῆς μάλιστα νοσῆσαν σῶμα συνεχῆ καύματα καὶ πυρετοὺς ἀπεργάζεται͵ τὸ δ΄ ἐξ ἀέρος ἀμφημερινούς͵ τριταίους δ΄ ὕδατος διὰ τὸ νωθέστερον ἀέρος καὶ πυρὸς αὐτὸ εἶναι· τὸ δὲ γῆς͵ τετάρτως ὂν νωθέστατον τούτων͵ ἐν τετραπλασίαις περιόδοις χρόνου καθαιρόμενον͵ τεταρταίους πυρετοὺς ποιῆσαν ἀπαλλάττεται μόλις.