In the following years the plan of a Council enabled Charles to keep the Papacy in all essential points under his control, and at one and the same time to protect and to oppress it. The greatest danger of all- -secularization - the danger which came from within, from the Popes themselves and their 'nipoti,' was adjourned for centuries by the German Reformation. Just as this alone had made the expedition against Rome (1527) possible and successful, so did it compel the Papacy to become once more the expression of a world-wide spiritual power, to raise itself from the soulless debasement in which it lay, and to place itself at the head of all the enemies of this reformation. The institution thus developed during the latter years of Clement VII, and under Paul III, Paul IV, and their successors, in the face of the defection of half Europe, was a new, regenerated hierarchy, which avoided all the great and dangerous scandals of former times, particularly nepotism, with its attempts at territorial aggrandizement, and which, in alliance with the Catholic princes, and impelled by a newborn spiritual force, found its chief work in the recovery of what had been lost. It only existed and is only intelligible in opposition to the seceders. In this sense it can be said with perfect truth that the moral salvation of the Papacy is due to its mortal enemies. And now its political position, too, though certainly under the permanent tutelage of Spain, became impregnable; almost without effort it inherited, on the extinction of its vassals, the legitimate line of Este and the house of Della Rovere, the duchies of Ferrara and Urbino. But without the Reformation - if, indeed, it is possible to think it away - the whole ecclesiastical State would long ago have passed into secular hands.
